Nature’s Miracle Stain Remover vs Simple Solution Extreme Eliminator Spray

Battle pet stains effectively! We tested 7 top removers to find the best solutions for spotless homes. Discover which products truly shine.

Nature’s Miracle Stain Remover and Simple Solution Extreme Eliminator Spray dominate the enzymatic cleaner market, but they serve entirely different households. Nature’s Miracle provides a gentle, citrus-scented daily defense against standard dog accidents, while Simple Solution delivers a professional-strength formula for severe, multi-pet messes.

In our testing, we found Simple Solution’s formula is noticeably stronger on set-in stains, whereas Nature’s Miracle excels at immediate, light cleanups. We compared their enzymatic breakdown capabilities to determine which spray belongs under your sink.

1
Nature’s Miracle Everyday Stain & Odor Remover
Best for Daily Spot Cleaning
Nature’s Miracle Everyday Stain & Odor Remover
Quickly breaks down fresh pet messes with a powerful enzymatic formula.
8.3
Amazon.com
2
Simple Solution Extreme Pet Stain & Odor Eliminator
More Versatile Applicator
Simple Solution Extreme Pet Stain & Odor Eliminator
A 3X stronger pro-bacteria formula that eliminates both new and old pet stains.
9
Amazon.com

Best for Daily Spot Cleaning

Nature’s Miracle Everyday Stain & Odor Remover

Quickly breaks down fresh pet messes with a powerful enzymatic formula.
8.3/10
EXPERT SCORE
This spot remover is your go-to for daily pet accidents. The enzymatic formula begins to break down stains immediately on contact and keeps working as long as bio-based material is present. It leaves behind a light citrus scent to get your home smelling clean again. This 32-ounce formula is intended for everyday messes, not set-in stains.
Starts breaking down stains immediately on contact
Enzymatic formula keeps working on bio-based messes
Leaves behind a light citrus scent
Formulated for fresh stains, not set-in messes
Intended for spot cleaning only

Nature’s Miracle Stain and Odor Remover targets everyday dog messes. The formula begins breaking down stains immediately on contact with the soiled area. It relies on an enzymatic formula that continues working as long as bio-based material remains in the carpet fibers, making it highly effective for standard urine and vomit accidents. The spray is safe around pets and your home when stored as directed.

This cleaner features a light citrus scent that controls dog odor naturally rather than masking smells with heavy perfumes. The enzymes actively consume odor-causing bacteria until the mess is gone. Users simply saturate the area and let it air dry.

Nature’s Miracle handles standard daily accidents rather than extreme or set-in stains. It serves as an excellent first line of defense for a new puppy in training, though it requires extra applications for older or severe messes. The citrus scent is pleasant, but sensitive noses might prefer an unscented alternative.


More Versatile Applicator

Simple Solution Extreme Pet Stain & Odor Eliminator

A 3X stronger pro-bacteria formula that eliminates both new and old pet stains.
9/10
EXPERT SCORE
Tackle the toughest pet messes with this professional-strength enzymatic cleaner. It's three times stronger than the regular formula, allowing it to neutralize even old, set-in stains. The patented 3-in-1 nozzle lets you choose between mist, foam, or stream for targeted cleaning, but it's only for use on water-safe surfaces.
3X stronger formula tackles old and new stains
Features a 3-in-1 nozzle (mist, foam, stream)
Safe for carpets, upholstery, bedding, and more
Only for use on water-safe surfaces
Requires manual scrubbing for best results

Simple Solution Extreme Pet Stain and Odor Remover tackles severe biological stains. This professional-strength spray consists of a powerful enzyme formula that is three times stronger than standard cleaners. It uses a combination of pro-bacteria and enzymes to treat fresh accidents and older problem areas, offering a heavy-duty approach for homes requiring extra cleaning power.

This multifunction spray works safely on carpets, upholstery, bedding, fabric toys, clothing, and other water-safe surfaces. The formula targets proteins in pet waste to eliminate the root cause of the smell. Breaking down these proteins discourages pets from returning to the same spot to mark again.

Simple Solution Extreme delivers significantly more raw cleaning power than Nature’s Miracle. The stronger formula suits households with multiple pets or frequent heavy accidents. It is explicitly formulated for both dogs and cats, unlike dog-specific alternatives. Single-pet homes may not require this level of strength, but it effectively removes stubborn stains that standard cleaners leave behind.


Enzymatic Strength

Enzymatic cleaners use helpful bacteria to produce enzymes that consume organic material like urine and vomit. Standard formulas work well for fresh, daily accidents, while professional-strength options with pro-bacteria blends are necessary for older, set-in stains.

Surface Versatility

Check if the spray is safe for multiple water-safe surfaces. While most cleaners handle carpets, versatile formulas can also treat upholstery, bedding, fabric toys, and clothing.

Pet-Specific Formulas

Some cleaners target specific biological waste. Dog-specific formulas often include citrus scents for odor control, whereas multi-pet households benefit from heavy-duty sprays formulated for both dog and cat messes.

Conclusion

Buy Nature’s Miracle for fresh, daily dog accidents on carpets. Choose Simple Solution Extreme if you manage a multi-pet household with stubborn, set-in stains across various fabrics. Assess your pet’s mess frequency and purchase the appropriate enzymatic cleaner today.

Frequently Asked Questions

How do enzymatic cleaners work on pet stains?

Enzymatic cleaners contain helpful bacteria that produce enzymes to break down biological waste like urine and vomit. These enzymes continue working to consume the organic material until the mess and odor are completely gone.

Can I use these sprays on my couch?

Yes, both of these products are generally safe for water-safe fabrics and upholstery. You should always test a small hidden area of your couch first to ensure the fabric is colorfast.

Do I need to scrub the stain after spraying?

You do not usually need to scrub aggressively when using an enzymatic cleaner. It is best to saturate the area, let the enzymes sit and do their work, and then blot up the excess moisture with a clean towel.

Will these sprays stop my dog from marking the same spot?

Yes, by completely breaking down the odor-causing proteins, these sprays remove the scent markers that attract pets back to the same area. This helps prevent repeat marking behaviors in your home.